A targeted 40% reduction in calorie consumption could slow down cell maturation and even delay life span, studies have recommended. Currently, analysts claim to have found out how to reflect the valuable effects of calorie restriction on the mind with a drug.
The pill contains a chemical in synapses, and research has shown that the drug has shifted both the mental retardation associated with maturation and Alzheimer’s disease and the lack of nerve cells that occurs with maturation.
The new study was carried out in mice, but recommends that researchers develop drugs that combat the decline in human mental functioning.
“There are clear effects on human wellbeing,” said Coleen Murphy, a Princeton University teacher who studies maturation but was not associated with the new test.
Most of the previous caloric restriction studies were conducted on mice and various living creatures used for laboratory testing. However, concentrates in humans have shown that calorie restriction can support the memory of older people.
In the new research, specialists from the Massachusetts Institute of Technology looked at how calorie restriction affects the synapses. They showed that limiting the calorie intake of mice at the research centre by 30% increased catalyst levels in the cerebrum and postponed the lack of nerve cells that can be associated with a decrease in mental work.
The low-calorie mice also improved over memory tests, contrasted and cared a lot about partners.
At this point, the analysts mimicked the calorie restriction – they looked after the mice with a normal eating routine, but additionally gave them the chemically inhibiting drugs. These mice are well suited to work with synapses and improve psychological tests, similar to the mice that have a calorie-reduced dietary regime.
This study is the first to show that the benefit of calorie restriction of intellectual capacity is associated with less neuronal degeneration.
This is also the main representation of a technical atom that mimics the benefits of calorie restriction, said David Sinclair, a teacher at Harvard Medical School who recently joined forces with developers to mature the research.
“This makes it all the more fascinating that the [drug] has anticipated neurodegeneration, one of the most difficult degenerative cycles to reverse with a drug,” Sinclair said.
Regardless of whether calorie restriction could expand the scope of human existence, it is not clear. Studies of mice and other exploratory animals, such as roundworms, have shown increases in life expectancy. However, studies conducted over 20 years in monkeys have had conflicts. Investigations in humans would take much longer, and if everything is the same, relatively few people are likely to find a stable state of fractional hunger, whether or not this delays their lives.
The likely benefits of calorie restriction for the well-being of the cerebrum also need further investigation, the analysts said. Significantly more work is needed to understand whether increasing the level of a chemical by taking a pill could allow the human mind to work better at a mature age, and whether such a pill could prevent or even counteract the adjustments in the cerebrum of Alzheimer’s patients.
No such pill is likely to be without its own results or complete prevention of disease, warned Li-Huei Tsai and Johannes Gräff, the main creators of the new study.
“Our results show that we can postpone neurodegeneration, but that is still far from really preventing it,” Tsai said. “Probably, drugs will always be unable to absolutely prevent an infection, but as long as their onset can be postponed, this is all we can look for”.
The new study will be published today (22 May) in the Journal of Neuroscience.
Pass it on: Scientists have reached a stage where they can postpone the intellectual decline associated with maturation and Alzheimer’s disease
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